Studies on vitamin E. 2. Reversal of respiratory decline in nutritional liver necrosis by intraportal administration of tocopherols and other substances.
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چکیده
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منابع مشابه
Reversal of respiratory decline in necrotic liver degeneration by intraportal tocopherols.
Necrotic liver degeneration is produced in rats by diets deficient in vitamin E, cystine, and Factor 3 (1). During the latent phase of the disease, several weeks before the onset of acute hepatic necrosis, a defect in oxidative metabolism has been demonstrated in livers of animals on such diets. oxygen consumption of histologically unaffected liver slices breaks down after a brief initial perio...
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Rat-liver slices lose potassiumwhenplaced in cold saline solution and reaccumulate potassium when placed in warm oxygenated Ringer solution (McLean, 1963). Weanling rats fed on a yeast diet which is deficient in vitamin E and selenium suffer acute liver necrosis at 17 ± 4 days after starting to eat the diet. Liver slices taken from rats given this diet for 7 days or more cannot reaccumulate pot...
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عنوان ژورنال:
- The Biochemical journal
دوره 75 شماره
صفحات -
تاریخ انتشار 1960